Prof. Dr. Betül Tuğcu
Prof. Dr. Betül Tuğcu
Education and Specialization
Istanbul University Cerrahpaşa Faculty of Medicine, English Program – Medical Degree (1996)
Bezmiâlem Valide Sultan Vakıf Gureba Training and Research Hospital, Ophthalmology Clinic – Residency (2001)
Bakırköy Dr. Sadi Konuk Training and Research Hospital Eye Clinic – Associate Professorship (2014)
Bezmialem Vakıf University Faculty of Medicine – Professorship (2020)
Experience
2001–2014 Bakırköy Dr. Sadi Konuk Training and Research Hospital Eye Clinic
2014–2025 Bezmialem Vakıf University Faculty of Medicine
Liv Hospital Ulus – Ophthalmology
Areas of Interest
Strabismus and ocular motility disorders
Amblyopia
Botulinum toxin applications
Neuro-ophthalmology
Retina and optical coherence tomography
Cataract and general ophthalmology
Pediatric ophthalmology, myopia control and diplopia.
Professional Memberships
Turkish Ophthalmological Association.
International Strabismological Association (ISA).
European Strabismological Association (ESA).
Courses and Certificates
2012: Training of Trainers Program, Istanbul.
2014: Strabismus training, Hacettepe University Department of Ophthalmology.
Scientific Publications
Articles
Ozbas C, Kirik F, Akbulut E, Karakayali ZC, Tugcu B, Ozdemir MH. Subfoveal and Peripapillary Choroidal Assessment in Multiple Sclerosis with Unilateral Optic Neuritis. Curr Eye Res. 2026 Aug;51(8):1006-1011. doi: 10.1080/02713683.2026.2659889. Epub 2026 Apr 19. PMID: 42001269.
Bayraktar H, Ekinci Aslanoğlu C, Tuğcu B. Structural Evaluation of Retinal and Choroidal Features in Eyes With Primary Microtropia. J Pediatr Ophthalmol Strabismus. 2026 Oct 16:1-8. doi: 10.3928/01913913-20260806-01. Online ahead of print. PMID: 42885601.
Yıldırım H, Sönmezay E, Tugcu B. Management of childhood cyclic esotropia with botulinum toxin. J Fr Ophtalmol. 2026 Jan;49(1):104711. doi: 10.1016/j.jfo.2025.104711. Epub 2025 Dec 10. PMID: 41380343.
Tugcu B, Yildirim H, Kunduracı MS, Akbulut E, Ersan BA. Botulinum Toxin A for Management of Consecutive Exotropia: Factors Affecting Treatment Success. J Pediatr Ophthalmol Strabismus. 2025 Jul-Aug;62(4):258-269. doi: 10.3928/01913913-20250117-02. Epub 2025 Feb 19. PMID: 39969476.
Ozbas C, Kirik F, Akbulut E, Eldemir G, Tugcu B, Ozdemir MH. Differentiation of optic disc edema and pseudopapilledema with deep learning on near-infrared reflectance images. BMC Ophthalmol. 2025 Oct 22;25(1):591. doi: 10.1186/s12886-025-04423-y. PMID: 41126114.
Tugcu B, Araz-Ersan B, Özkan SB. Botulinum toxin A for the treatment of strabismus in children with neurological impairment. Arq Bras Oftalmol. 2023 Mar 24;87(4):e2021-0401. doi: 10.5935/0004-2749.2021-0401. Online ahead of print. PMID: 36995810.
AKBULUT E., KIRIK F., BAYRAKTAR H., MOHAMMED A. R., TUĞCU B. Yapay Zekâ Modeli ile Şaşılığın Saptanmasında Optimum Hiperparametrelerin Belirlenmesi: Kesitsel Araştırma Türkiye Klinikleri Oftalmoloji Dergisi , cilt.32, sa.3, ss.176-183, 2023 (TRDizin) DOI: 10.5336/ophthal.2023-96253.
Tugcu B, Bayraktar H, Ekinci C, Kucukodaci Z, Tunali M, Nuhoglu F. The effect of platelet-rich fibrin on wound healing following strabismus surgery. Cutan Ocul Toxicol. 2022 Jun;41(2):168-173. doi: 10.1080/15569527.2022.2081173. Epub 2022 Jun 12. PMID: 35694975.
Kunduracı MS, Kantarcı B, Araz Erşan HB, Tuğcu B. Use of Botulinum Toxin A in the Treatment of Intermittent Exotropia: Factors Affecting Treatment Outcome. Semin Ophthalmol. 2022 Jul 4;37(5):626-630. doi: 10.1080/08820538.2022.2048031. Epub 2022 Mar 7. PMID: 35254211.
Hamurcu M, Ekinci C, Koca S, Tugcu B. Evaluation of amblyopic eyes with optical coherence tomography angiography and electrophysiological tests. Indian J Ophthalmol. 2021 Jan;69(1):105-110. doi: 10.4103/ijo.IJO_2319_19. PMID: 33323589.
Kaya Tutar N, Kale N, Tugcu B. Adie-Holmes syndrome associated with COVID-19 infection: A case report. Indian J Ophthalmol. 2021 Mar;69(3):773-774. doi: 10.4103/ijo.IJO_3589_20. PMID: 33595525.
Paraneoplastic optic neuropathy as an initial clinical manifestation of small cell lung cancer. a case report. Akbulut E, Bayraktar H, Tugcu B. Česká a slovenská oftalmologie 2021,5; 300-303.
Tugcu B, Melikov A, Yildiz GB, Gökcal E, Ercan R, Uysal O, Ozdemir H. Evaluation of retinal alterations in Parkinson disease and tremor diseases. Acta Neurol Belg. 2020 Feb;120(1):107-113. doi: 10.1007/s13760-019-01228-x. Epub 2019 Nov 2. PMID: 31679150.
Nuhoglu F., Tugcu B. C., Tunali M., Ozdemir H. Effectiveness of Titanium-Platelet-Rich Autograft: A Preliminary Report JOURNAL OF ACADEMIC RESEARCH IN MEDICINE-JAREM , cilt.8, sa.2, ss.91-95, 2018 (ESCI, TRDizin) DOI: 10.5152/jarem.2018.1908.
TUĞCU B., nacaroğlu aşık s., evcimen y., TAŞKAPILI M. Şaşılık Cerrahisinin Nadir Bir Komplikasyonu: Koroidal Efüzyon MN Oftalmoloji , 2018 (TRDizin)
Tuğcu B, Bitnel MK, Kaya FS, Güveli BT, Ataklı D. Evaluation of inner retinal layers with optic coherence tomography in vigabatrin-exposed patients. Neurol Sci. 2017 Aug;38(8):1423-1427. doi: 10.1007/s10072-017-2971-0. Epub 2017 May 16. PMID: 28508989.
Tugcu B, Nacaroglu SA, Gedikbasi A, Uhri M, Acar N, Ozdemir H. Protective effect of pomegranate juice on retinal oxidative stress in streptozotocin-induced diabetic rats. Int J Ophthalmol. 2017 Nov 18;10(11):1662-1668. doi: 10.18240/ijo.2017.11.05. eCollection 2017. PMID: 29181308.
Tuğcu B, Sönmezay E, Nuhoğlu F, Özdemir H, Özkan SB. Botulinum toxin as an adjunct to monocular recession-resection surgery for large-angle sensory strabismus. J AAPOS. 2017 Apr;21(2):117-120. doi: 10.1016/j.jaapos.2017.03.008. Epub 2017 Mar 16. PMID: 28315737.
Tugcu BL, Sezer T, Elbay A, Özdemir H. Angioid streaks in a case of Camurati-Engelmann disease. Indian J Ophthalmol. 2017 Jul;65(7):628-630. doi: 10.4103/ijo.IJO_910_16. PMID: 28724827.
TUĞCU B., ekinci c., şen a. Normal kranyal manyetik rezonans incelemesi olan bir Tolosa-hunt sendromu olgusu MN Oftalmoloji , 2017 (TRDizin)
TUĞCU B., ekinci c., şen a. Parkinson hastalığında göz bulguları MN Oftalmoloji , 2017 (TRDizin)
Tuğcu B, Özdemir H. Imaging Methods in the Diagnosis of Optic Disc Drusen. Turk J Ophthalmol. 2016 Oct;46(5):232-236. doi: 10.4274/tjo.66564. Epub 2016 Oct 17. PMID: 28058166.
Sefi-Yurdakul N, Tuğcu B. Development of Strabismus in Children Initially Diagnosed with Pseudostrabismus. Strabismus. 2016 Jun;24(2):70-3. doi: 10.3109/09273972.2016.1170046. Epub 2016 May 24. PMID: 27220260.
Acet Y, Yigit FU, Onur IU, Agachan A, Tugcu B, Orum O. The Course of the Changes in Anterior Chamber Parameters After Laser Peripheral Iridotomy: Follow-up for 6 Months With a Scheimpflug-Placido Disc Topographer. J Glaucoma. 2016 Jan;25(1):14-21. doi: 10.1097/IJG.0000000000000068. PMID: 24844539.
Tuğcu B., Nuhoğlu F., Melikov A., Özdemir M. H. Eğik optik disk. Türkiye Klinikleri Oftalmoloji Dergisi , cilt.6, ss.246-252, 2016 (TRDizin)
Tugcu B, Nacaroglu SA, Coskun C, Kuscu DY, Onder F. Chronic Meningitis Complicating Intracranial Hypertension in Neurobrucellosis: A Case Report. Semin Ophthalmol. 2015;30(5-6):429-31. doi: 10.3109/08820538.2013.874472. Epub 2014 Feb 7. PMID: 24506671.
Yurtsever B, Çabalar M, Kaya H, Tuğcu B, Yazıcı ZM, Yayla V. A Rare Cause of Hearing Loss: Susac Syndrome. J Int Adv Otol. 2015 Aug;11(2):167-9. doi: 10.5152/iao.2015.1002. PMID: 26381010.
Yalcinkaya EY, Caglar NS, Tugcu B, Tonbaklar A. Rehabilitation outcomes of children with cerebral palsy. J Phys Ther Sci. 2014 Feb;26(2):285-9. doi: 10.1589/jpts.26.285. Epub 2014 Feb 28. PMID: 24648650.
Sen A, Tugcu B, Coskun C, Ekinci C, Nacaroglu SA. Effects of levodopa on retina in Parkinson disease. Eur J Ophthalmol. 2014 Jan-Feb;24(1):114-9. doi: 10.5301/ejo.5000338. Epub 2013 Jul 3. PMID: 23828323.
Tugcu B, Araz-Ersan B, Erdogan ET, Tarakcioglu H, Coskun C, Yigit U, Karamursel S. Structural and functional comparison of the persistent and resolved amblyopia. Doc Ophthalmol. 2014 Apr;128(2):101-9. doi: 10.1007/s10633-013-9422-x. Epub 2013 Dec 18. PMID: 24343574.
Tugcu B, Acar N, Coskun CT, Celik S, Yigit FU. Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome. Indian J Ophthalmol. 2014 May;62(5):642-4. doi: 10.4103/0301-4738.109535. PMID: 23571268.
Tugcu B, Araz-Ersan B, Kilic M, Erdogan ET, Yigit U, Karamursel S. The morpho-functional evaluation of retina in amblyopia. Curr Eye Res. 2013 Jul;38(7):802-9. doi: 10.3109/02713683.2013.779721. Epub 2013 Mar 22. PMID: 23521720.
Tugcu B, Helvacioglu F, Yuzbasioglu E, Gurez C, Yigit U. Amniotic membrane in the management of strabismus reoperations. Jpn J Ophthalmol. 2013 Mar;57(2):239-44. doi: 10.1007/s10384-012-0217-5. Epub 2012 Dec 13. PMID: 23233195.
Tugcu B, Araz-Ersan B, Eren G, Selçuk H, Yigit U. Transient cortical blindness after spinal surgery as initial presenting sign of hereditary thrombophilia. Indian J Ophthalmol. 2013 Mar;61(3):139-40. doi: 10.4103/0301-4738.97565. PMID: 23514658.
Ulviye Y, Betul T, Nur TH, Selda C. Spectral domain optical coherence tomography for early detection of retinal alterations in patients using hydroxychloroquine. Indian J Ophthalmol. 2013 Apr;61(4):168-71. doi: 10.4103/0301-4738.112161. PMID: 23685488.
Tugcu B, Soysal A, Kılıc M, Yuksel B, Kale N, Yıgıt U, Arpaci B. Assessment of structural and functıonal vısual outcomes ın relapsıng remıttıng multıple sclerosıs wıth vısual evoked potentıals and optıcal coherence tomography. J Neurol Sci. 2013 Dec 15;335(1-2):182-5. doi: 10.1016/j.jns.2013.09.027. Epub 2013 Oct 1. PMID: 24148562.
Soysal A, Yüksel B, Czermin B, Aydemir S, Tuğcu B, Aysal F, Arpaci B. Case study of sporadic mitochondrial disease with myotonic discharges and optic atrophy. Muscle Nerve. 2013 Feb;47(2):308-9. doi: 10.1002/mus.23641. PMID: 23349087.
İşcan Y, Yiğit U, Tuğcu BÇ, Erdoğan M, Erdoğan DA, Öner V, Taş M, Özyazgan Y. Tear nitric oxide levels in Behçet's disease. Medicina (Kaunas). 2012;48(11):559-62. PMID: 23455889.
Tugcu B, Helvacıoğlu F, Yüzbaşıoğlu E, Gürez C. The use of amniotic membrane in the management of strabismus reoperation cases. J Clinic Experiment Ophthalmol 2011; 2(5): 1-4.
Şen A, Tuğcu B, Soysal A, Yüksel B, Kocabıyık N, Arpacı B. Choroidal tuberculoma in two cases with multiple intracranial tuberculomas. Journal of Neurological Sciences (Turkish) 2011; 28(4): 609-613
Sevketoglu E, Tatlı B, Tugcu B, Demirelli, Hatipoğlu S. Angel’s Trumpet-associated polyneuropathy- Is it Guillain-Barré Syndrome? Pediatric Neurology 2011; 45: 63-64.
Sevketoglu E, Tatlı B, Tuğcu B, Demirelli Y, Hatipoglu S. An unusual cause of fulminant Guillain-Barré syndrome: angel's trumpet. Pediatr Neurol. 2010 Nov;43(5):368-70. doi: 10.1016/j.pediatrneurol.2010.05.019. PMID: 20933184.
Yuzbasioglu E, Helvacioglu F, Tugcu B, Terzi N, Keskinbora K. The results of cataract nigra cases operated with the mini-nuc technique. Int Ophthalmol. 2009 Dec;29(6):451-7. doi: 10.1007/s10792-008-9265-8. Epub 2008 Oct 16. PMID: 18923815.
Yuzbasioglu E, Tugcu B, Artunay O, Helvacıoglu F. Effects of periocular massage by Breeze on ocular blood flow and intraocular pressure. Journal of Chinese Clinical Medicine 2008; 3(6): 333-342.
Conference Presentations and Proceedings
Botulinum Toxin Treatment of Consecutive Exotropia Tuğcu B, Yıldırım H, Erşan B, Kunduracı MS, Akbulut E. Joint Meeting of the European and International Strabismological Associations 2024, Toulouse.
Management of chıldhood cyclıc esotropıa wıth botulınum toxın treatment. Tuğcu B, Yıldırım H, Sonmezay E. Joint Meeting of the European and International Strabismological Associations 2024, Toulouse.
Tuğcu B, Erşan B, Yalçınkaya EY, Özkan SB. Botulinum Toxin A for the treatment of variable angle strabismus in neurologically impaired children. 39th Meeting of the European Strabismological Association 2017, Porto
Tugcu B, Selin, Ataklı D. "Evaluation Of Retinal Nerve Fiber Layer With Optic Coherence Topography in Patients Using Vigabatrin" poster presentation at the 31st International Epilepsy Congress (IEC) in Istanbul 5-9 September 2015.
Kale N, Özdemir Z, Özerdem M, Kara B, Kaya S, Tugcu B, Soysal A.The clinical and demographic features of patients with intracranial hypertension, what is the effect of weight loss in disease prognosis. European Academy of Neurology 2015, poster presentation.
Tuğcu B, Soysal A, Acet Y, Yüksel B, Yiğit U, Arpacı B. Assesment of the effect of disease modifiying treatment in Multiple Sclerosis:1 year follow up results.16th Afro-Asian Congress of Ophthalmology-5th Mediteranean Retina Meeting, İstanbul, 2012.
Tuğcu B, Araz Erşan B, Gülkılık G, İnci E, Yiğit U. Management of medial rectus muscle paresis complicating functional endoscopic sinus surgery with botulinum. VIII.Congress of the South-East European Ophthalmological Society- IX.Congress of the Black Sea Ophthalmological Society, İstanbul 2011.
Tuğcu B, Soysal A, Kılıç M, Araz Erşan B, Yüksel B, Yiğit U, Arpacı B. Assesment of the effect of disease modifying treatment in multiple sclerosis. VIII. Congress of the South-East European Ophthalmological Society- IX.Congress of the Black Sea Ophthalmological Society, İstanbul 2011.
Ağaçhan A, Özkaya A, Yiğit U, Tuğcu B, Onur İ, İşcan Y. A patient with secondary glaucoma due to herpetic keratouveitis and dependent on acyclovir therapy. 15th ESCRS Winter Meeting, İstanbul 2011.
Özkaya A, Ağaçhan A, Yiğit U, Tuğcu B, Onur İ, İşcan Y. A patient with recurrent herpetic stromal keratitis who is dependent on systemic acyclovir therapy. 15th ESCRS Winter Meeting, İstanbul 2011.
Tuğcu Çakmak B, Kılıç M, Erdoğan E T, Yiğit U, Karamürsel S. Structure-function relationship in amblyopia: Assesment of retina ganglion cells by OCT and pattern ERG. XI th International Strabismological Association, İstanbul 2010.
Tuğcu Çakmak B, Örüm Ö, Ziylan Ş, Camuşçu H, Hocaoğlu E. Ocular motility improvement in Crouzon Syndrome after neurosurgical intervention without any strabismus operation. XI th International Strabismological Association, İstanbul 2010.
Tuğcu Çakmak B, Gürez C, Yiğit U. Comparison of atropin-optical penelization versus occlusion for moderate amblyopia. XI th International Strabismological Association, İstanbul 2010.
Tuğcu Çakmak B, Kılıç M, Erdoğan E T, Ağaçhan A, Yiğit U, Karamürsel S. The effect of optic disc factors on retina nerve fiber layer analysis and pattern ERG parameters in amblyopia. XI th International Strabismological Association, İstanbul 2010.
Tuğcu Çakmak B, Gürez C, Yiğit U. Evaluation of the development of fusion and stereoacuity after surgical treatment in cases with infantile esotropia. XI th International Strabismological Association, İstanbul 2010.
Yiğit U, Özdemir S, Tuğcu Çakmak B, Ağaçhan A. The effect of fusion on surgical success in patients with concomitant esotropia. XI th International Strabismological Association, İstanbul 2010.
Yiğit U, Tuğcu Çakmak B, Özdemir S. The effect of preoperative angle of deviation on surgical success in patients with concomitant esotropia. XI th International Strabismological Association, İstanbul 2010.
Agaçhan A, Yuzbaşıoğlu E, Tugcu B, Ozdemir S,Yigit U. The efficiency of topical 0.05% cyclosporin A in a dry eye treatment. 9th Congress of the International Society of Dacryology and Dry Eye, İstanbul 2008.
Tanrıverdi Ç, Tuğcu B, Önder F, Sencan S. Persistent visual loss in pseudotumor cerebri with neurobrucellosis. 8th European Neuro-Ophthalmology Society (EUNOS) Meeting, İstanbul 2007.
Yuzbasioglu E, Helvacioglu F, Sencan Ş, Tugcu B, Yıldırım H. Cataract surgery in a case with nonophthalmos. XXIV Congress of the ESCRS, London 2006.
Helvacioglu F, Tugcu B, Yuzbasioglu E, Tanriverdi Ç, Sencan S. The comparison of preoperative subconjunctival mitomycin C application and superior temporal limbal conjunctival autografting to prevent recurrence of pterygium. XXIV Congress of the ESCRS, London 2006.
Tugcu B, Helvacioglu F, Yuzbasioglu E, Gurez C, Sencan S. Two year results of pterygium surgery combined by superior temporal limbal conjunctival autografting. XXIV Congress of the ESCRS, London 2006.
Tugcu B, Helvacioglu F, Seylan M, Gürez C, Sencan S. One and a half year results of preoperative subconjunctival mitomycin C application to prevent recurrence of pterygium. Black Sea Ophthalmological Society 3rd International Congress, İstanbul 2005.
Tugcu B, Seçkin İ, Sencan S, Ertürk ÜP, Helvacioglu F. The clinic, the systemic, the metabolic and the electron microscopic evaluation of a case with christmas tree cataracts. Black Sea Ophthalmological Society 3rd International Congress, İstanbul 2005.
Tuğcu B, Terzi N, Helvacıoğlu F, Keskinbora K, Şencan S. The significance of risk factors in retinopathy of prematurity. VIII. Mediterranean Ophthalmology Society Congress, Antalya 2004.
Helvacıoğlu F, Tuğcu B, Şencan S. Clinical surgical approach to scleromalacia developed after pterjium surgery with intraoperative and preoperative mitomycin C application. XXIV Congress of the ESCRS, Paris 2004.
Appointments and Contact
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