Assoc. Prof. Dr. Edin Botan

Pediatrics

Pediatric Intensive Care

Cumhuriyet University Faculty of Medicine, 2007

İnönü University, Pediatrics, 2008-2013

Ankara University, Pediatric Intensive Care fellowship, 2018-2021

2007–2008 — Muradiye Devlet Hastanesi

2008–2013 — İnönü Üniversitesi Tıp Fakültesi Turgut Özal Tıp Merkezi

2013–2014 — Elazığ Eğitim ve Araştırma Hastanesi

2014–2016 — Van Özel Lokman Hekim Hastanesi

2016–2018 — Erciş Med Tıp Merkezi, Van

2018–2021 — Ankara Üniversitesi Tıp Fakültesi

2021–2024 — Van Eğitim ve Araştırma Hastanesi

09.2024–09.2025 — Yeni Yüzyıl Üniversitesi Gaziosmanpaşa Hastanesi

09.2025 — İstinye Üniversitesi Tıp Fakültesi Hastanesi

Management of critically ill children

Central venous catheter placement

Continuous hemodialysis (CVVHD) in neonatal and pediatric patients

Plasma exchange in pediatric patients

Chest tube placement in pediatric patients

ECMO monitoring and management in children

Palliative pediatric follow-up

Pediatric outpatient care

Management of critically ill children with neurological disorders

Management of pediatric sepsis and septic shock

Management of severe respiratory failure in children

Echocardiographic assessment of cardiac function in critically ill patients

Ultrasound examination of the abdomen and chest in critically ill children

Gurbanov A, Kendirli T, Botan E, Kahveci F, Gencay AG, Arga G, Özdemir H, Çiftçi E. Serratia marcescens-Associated Ecthyma Gangrenosum in an Infant on Extracorporeal Life Support. Turk Arch Pediatr. 2022 Jul;57(4):471-472. doi: 10.5152/TurkArchPediatr.2022.22037. PMID: 35822483.

Gün E, Botan E, Özdemir H, Kendirli T. Succesful treatment of COVID-19 infection in a child with tracheostomy. Tuberk Toraks. 2021 Jun;69(2):285-287. doi: 10.5578/tt.20219820. PMID: 34256521.

Öztürk AG, Küçük ZE, Özcan S, Havan M, Gün E, Botan E, Kendirli T. Use of Therapeutic Plasma Exchange in the Pediatric Intensive Care Unit. Turk Arch Pediatr. 2022 Mar;57(2):186-192. doi: 10.5152/TurkArchPediatr.2022.21209. PMID: 35383013.

Süzen-Orhan E, Botan E, Gün E, Özen H, Gurbanov A, Balaban B, Kahveci F, Vatansever G, Tekin D, Kendirli T. Colchicine Poisoning Cases in a Pediatric Intensive Care Unit: A Twenty-Year Study. Pediatr Emerg Care. 2022 Oct 1;38(10):489-493. doi: 10.1097/PEC.0000000000002835. Epub 2022 Aug 26. PMID: 36018729.

Botan E, Durak Aslan A, Gün E, Havan M, Dikmen N, Gurbanov A, Balaban B, Kahveci F, Özen H, Uçmak H, Can ÖS, Karagözlü S, Sarıcaoğlu MC, Eyileten Z, Uçar T, Tutar E, Akar AR, Uysalel MA, Kendirli T. Extracorporeal Membrane Oxygenation after Pediatric Cardiac Surgery: A Single-Center Experience. Turk Arch Pediatr. 2024 Jul 1;59(4):358-363. doi: 10.5152/TurkArchPediatr.2024.23291. PMID: 39140771.

Ulgen Tekerek N, Dursun O, Asilioglu Yener N, Yildizdas D, Anıl AB, Kendirli T, Koker A, Karalok S, Aksoy A, Kinik Kaya E, Ekinci F, Incecik F, Olgac Dundar N, Durak F, Botan E, Havan M, Sahin S, Duman O, Haspolat S. Posttraumatic epilepsy in critically ill children with traumatic brain injury. Childs Nerv Syst. 2023 Nov;39(11):3207-3214. doi: 10.1007/s00381-023-06087-9. Epub 2023 Jul 22. PMID: 37480521.

Gün E, Kendirli T, Botan E, Özdemir H, Çiftçi E, Konca K, Koloğlu M, Göllü G, Can ÖS, Tutar E, Akar AR, İnce E. Temporary Diverting End-Colostomy in Critically Ill Children with Severe Perianal Wound Infection. Adv Skin Wound Care. 2021 Jun 1;34(6):322-326. doi: 10.1097/01.ASW.0000744332.84964.0f. PMID: 33979821.

Aydın B, Yılmaz HÇ, Botan E, Aktepe AÖ, Dilli D. Is it necessary to give calcium infusion during the exchange transfusion in newborns? Transfus Apher Sci. 2021 Dec;60(6):103236. doi: 10.1016/j.transci.2021.103236. Epub 2021 Aug 8. PMID: 34389203.

Botan E, Durak A, Gün E, Gurbanov A, Balaban B, Kahveci F, Özen H, Uçmak H, Aycan F, Kendirli T. Continuous Renal Replacement Therapy with Regional Citrate Anticoagulation in Children with Liver Dysfunction/Failure. J Trop Pediatr. 2022 Jun 6;68(4):fmac048. doi: 10.1093/tropej/fmac048. PMID: 35737953.

Botan E, Uyar E, Öztürk Z, Şevketoğlu E, Sarı Y, Dursun O, Sincar Ş, Duyu M, Oto A, Celegen M, Özçiftçi G, Havan M, Öztürk MN, Ağın H, Yener N, Yaman A, Gün E, Yılmaz M, Şimşek N, Özdemir H, Yıldızdaş D, Kendirli T. COVID-19 Transmission and Clinical Features in Pediatric Intensive Care Health Care Workers. Turk Arch Pediatr. 2022 Jan;57(1):93-98. doi: 10.5152/TurkArchPediatr.2022.21205. PMID: 35110085.

Kahveci F, Karaçoban G, Çelik NA, Gurbanov A, Uçmak H, Balaban B, Botan E, Dikmen N, Havan M, Ramoğlu MG, Eyileten Z, Uçar T, Kendirli T. Venovenous Versus Venoarterial Extracorporeal Membrane Oxygenation: Pediatric Acute Respiratory Distress Syndrome. Turk Arch Pediatr. 2023 Nov;58(6):600-606. doi: 10.5152/TurkArchPediatr.2023.23025. PMID: 37818844.

Gün E, Durak A, Botan E, Şimşek Pervane S, Gurbanov A, Balaban B, Kahveci F, Özen H, Uçmak H, Aycan F, Kuloğlu Z, Kendirli T. Extracorporeal Therapies in Children with Acute Liver Failure: A Single-Center Experience. Turk J Gastroenterol. 2023 Jan;34(1):73-79. doi: 10.5152/tjg.2022.22062. PMID: 36445055.

Kahveci F, Gurbanov A, Uçmak H, Ödemiş AS, Özen H, Balaban B, Botan E, Gün E, Havan M, Dikmen N, Ramoğlu MG, Uçar T, Eyileten Z, Akar AR, Kendirli T. Prolonged extracorporeal membrane oxygenation in pediatrics: How long did we wait? Perfusion. 2024 Jul;39(5):978-987. doi: 10.1177/02676591231172607. Epub 2023 May 3. PMID: 37137815.

Gün E, Kendirli T, Botan E, Türker N, Gurbanov A, Balaban B, Gencay AG, Arga G, Karagözlü S, Ramoglu MG, Özdemir H, Ucar T, Tutar E, Ciftci E. Multisystem Inflammatory Syndrome in Children Admitted to a Tertiary Pediatric Intensive Care Unit. J Pediatr Intensive Care. 2021 Aug 11;12(1):37-43. doi: 10.1055/s-0041-1733943. eCollection 2023 Mar. PMID: 36742251.

Gün E, Kendirli T, Öztürk AG, Botan E, Vatansever G, Arga G, Özdemir İ, Özdemir H, Tekin D, Çiftçi E, İnce E. Clinical Features and Outcomes of Children Admitted to the PICU due to Rotavirus Infection. Turk Arch Pediatr. 2021 Nov;56(6):591-595. doi: 10.5152/TurkArchPediatr.2021.21140. PMID: 35110058.

Yıldırım M, Bektaş Ö, Botan E, Şahin S, Gurbanov A, Teber S, Kendirli T. Therapeutic plasma exchange in clinical pediatric neurology practice: Experience from a tertiary referral hospital. Clin Neurol Neurosurg. 2021 Aug;207:106823. doi: 10.1016/j.clineuro.2021.106823. Epub 2021 Jul 17. PMID: 34304066.

Botan E, Gün E, Güneş SA, Gurbanov A, Özen H, Kuloglu Z, Kırsaçlıoğlu C, Kırımker EO, Selvi ÖC, Çiftçi E, Fitöz S, Koloğlu M, Kansu A, Balcı D, Kendirli T. Early period intensive care follow-up after liver transplantation in children: a single center experience. Turk J Pediatr. 2023;65(3):489-499. doi: 10.24953/turkjped.2022.743. PMID: 37395968.

Botan E, Gün E, Beşli Çelik D, Gurbanov A, Balsak S, Balaban B, Kahveci F, Özen H, Uçmak H, Gençay AG, Kendirli T. The Evaluation of Transported Children to Pediatric Intensive Care Unit: Indications, Problems, and Outcomes. Air Med J. 2021 Jul-Aug;40(4):237-241. doi: 10.1016/j.amj.2021.03.013. Epub 2021 May 6. PMID: 34172231.

Gün E, Özdemir H, Çelik DB, Botan E, Kendirli T. Saccharomyces cerevisiae fungemia due to an unexpected source in the pediatric intensive care unit. Turk J Pediatr. 2022;64(1):138-141. doi: 10.24953/turkjped.2020.1668. PMID: 35286041.

Kahveci F, Ocak BÖ, Gün E, Gurbanov A, Uçmak H, Aslan AD, Ceran A, Özen H, Balaban B, Botan E, Şıklar Z, Berberoğlu M, Kendirli T. Impact of the COVID-19 pandemic on diabetic ketoacidosis management in the pediatric intensive care unit. Acute Crit Care. 2023 Aug;38(3):371-379. doi: 10.4266/acc.2023.00038. Epub 2023 Aug 31. PMID: 37652866.

Gurbanov A, Kandemir H, Gurbanova L, Gün E, Botan E, Balaban B, Kahveci F, Özen H, Uçmak H, Özdemir İ, Havan M, Tekin D, Kendirli T. Antidepressant Poisoning Trends in Pediatric Intensive Care: A Comparative Study of New- and Old-Generation Antidepressants. J Clin Psychopharmacol. 2023 Mar-Apr 01;43(2):139-144. doi: 10.1097/JCP.0000000000001668. Epub 2023 Feb 16. PMID: 36795032.

Öztürk M, Botan E, Gün E, Baskin AK, İslamoğlu C, Erkol GH, Havan M, Çakmak FH, Haskoloğlu Ş, İleri T, İnce E, Doğu F, Ertem M, İkinciogullari A, Kendirli T. The Determining Factors for Outcome of Pediatric Intensive Care Admitted Children After Stem Cell Transplantation. J Pediatr Hematol Oncol. 2023 Aug 1;45(6):e768-e772. doi: 10.1097/MPH.0000000000002610. Epub 2022 Dec 19. PMID: 36706283.

Şahin S, Botan E, Gün E, Yüksel MF, Süt NY, Kartal AT, Gurbanov A, Kahveci F, Özen H, Havan M, Yıldırım M, Şahap SK, Bektaş Ö, Teber S, Fitoz S, Kendirli T. Correlation between early computed tomography findings and neurological outcome in pediatric traumatic brain injury patients. Neurol Sci. 2024 Sep;45(9):4417-4425. doi: 10.1007/s10072-024-07511-x. Epub 2024 Apr 15. PMID: 38622450.

Kendirli T, Kahveci F, Özcan S, Botan E, Sarıcaoğlu C, Hasde Aİ, Çakıcı M, Uçar T, Eyileten Z, Tutar E, Akar AR. Interhospital Aircraft/Ground Extracorporeal Membrane Oxygenation Transportation by a Mobile Extracorporeal Membrane Oxygenation Team: First Turkish Pediatric Case Series. Turk Arch Pediatr. 2022 Nov;57(6):656-660. doi: 10.5152/TurkArchPediatr.2022.22068. PMID: 36314958.

Gün E, Akova BŞ, Botan E, Çelik DB, Balaban B, Özen H, Gencay AG, Bektaş Ö, Fitoz S, Kendirli T. Clinical features and outcomes of children admitted to the pediatric intensive care unit due to posterior reversible encephalopathy syndrome. Clin Neurol Neurosurg. 2022 Nov;222:107476. doi: 10.1016/j.clineuro.2022.107476. Epub 2022 Oct 13. PMID: 36265243.

Özcan S, Akyüzlüer Güneş MS, Havan M, Perk O, Azapağası E, Gün E, Botan E, Ergun E, Ateş U, Kahiloğulları G, Kendirli T. Comparison of pre-PICU and per-PICU interventions, clinical features and neurologic outcomes of motor vehicle collision trauma and other mechanisms of trauma in children. Ulus Travma Acil Cerrahi Derg. 2022 Apr;28(4):456-463. doi: 10.14744/tjtes.2022.86617. PMID: 35485520.

Aydın B, Botan E, Gülensoy B, Akyol S. Hydranencephaly in a newborn due to occupational toluene exposure during pregnancy: a case report. Acute Crit Care. 2024 Nov;39(4):647-651. doi: 10.4266/acc.2021.01081. Epub 2022 Jul 15. PMID: 35977900.

Gün E, Gurbanov A, Nakip ÖS, Yöntem A, Aslan AD, Botan E, Kahveci F, Özcan S, Azapağası E, Emeksiz S, Yazıcı MU, Kesici S, Horoz ÖÖ, Erdeve Ö, Bayrakçı B, Yıldızdaş RD, Kendirli T. Clinical characteristics and outcomes of continuous renal replacement therapy performed on younger children weighing up to 10 kg. Turk J Med Sci. 2023 Jun;53(3):791-802. doi: 10.55730/1300-0144.5642. Epub 2023 Jun 19. PMID: 37476891.

Botan E, Gün E, Şden EK, Yöndem C, Gurbanov A, Balaban B, Kahveci F, Özen H, Uçmak H, Gençay AG, Kendirli T. Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience. Acute Crit Care. 2022 Nov;37(4):644-653. doi: 10.4266/acc.2022.00395. Epub 2022 Nov 11. PMID: 36442468.

Kahveci F, Gurbanov A, Uçmak H, Özen H, Balaban B, Botan E, Gün E, Kendirli T. The Dilemma of Pediatric Intensive Care Admissions During Coronavirus Disease 2019 Outbreak. Turk Arch Pediatr. 2023 Mar;58(2):232-233. doi: 10.5152/TurkArchPediatr.2023.22205. PMID: 36856364.

Kahveci F, Coşkun MK, Uçmak H, Özen H, Gurbanov A, Balaban B, Dikmen N, Karagözlü S, Sarıcaoğlu MC, Botan E, Gün E, Havan M, Ramoğlu MG, Uçar T, Eyileten Z, Tutar E, Akar AR, Kendirli T. Hybrid extracorporeal membrane oxynegation in pediatric intensive care patients: A single center experience: More is better? Perfusion. 2024 Jul;39(5):902-910. doi: 10.1177/02676591231168537. Epub 2023 Apr 3. PMID: 37010553.

Gün E, Kendirli T, Botan E, Uçar T, Aycan Z, Akar AR. Immobilization-induced symptomatic hypercalcemia treated with zoledronate in a child with a left ventricular assist device. Ann Pediatr Endocrinol Metab. 2021 Sep;26(3):205-209. doi: 10.6065/apem.2040206.103. Epub 2021 May 12. PMID: 34015907.

Boyraz M, Yüce S, Özel A, Örmeci MT, Akkaya S, Köksal Atiş Ş, Botan E. Identifying the need for surgical intervention in pediatric bacterial meningitis: single-center experience. Front Pediatr. 2025 Jul 16;13:1631570. doi: 10.3389/fped.2025.1631570. eCollection 2025. PMID: 40740821.

Botan E, Boyraz M, Yüce S, Erdem Torun Ş. Deadly Nightshade (Atropa belladonna) and Other Weed Poisonings in the Pediatric Intensive Care Unit: Analysis of 54 Children. Turk Arch Pediatr. 2024 Nov 1;59(6):580-585. doi: 10.5152/TurkArchPediatr.2024.23207. PMID: 39540784.

Boyraz M, Botan E, Yuce S, Erdem Torun Ş. Retrospective Evaluation of Poisoning Cases Followed Up in a Pediatric Intensive Care Unit-A 12-Year Experience in a Single Center. Pediatr Emerg Care. 2023 Oct 1;39(10):766-772. doi: 10.1097/PEC.0000000000003041. Epub 2023 Sep 4. PMID: 37665962.

Gurbanov A, Çelik NA, Gurbanova L, Gün E, Botan E, Balaban B, Kahveci F, Özen H, Uçmak H, Çağlayan U, Havan M, Vatansever G, Tekin D, Kendirli T. Clinical and Laboratory Features and Factors Determining the Outcome in Poisoning Children in a Tertiary Pediatric Intensive Care Unit: Eleven Years of Experience. Turk Arch Pediatr. 2023 Mar;58(2):189-196. doi: 10.5152/TurkArchPediatr.2023.22206. PMID: 36856357.

Havan M, Emekli B, Özcan S, Gün E, Botan E, Ramoğlu M, Karagözlü S, Dikmen N, Erdoğan BD, Uçar T, Eyileten Z, Tutar E, Uysalel A, Kendirli T. Evaluation of the Performance of Vasoactive Ventilation Renal Score in Predicting the Duration of Mechanical Ventilation and Intensive Care Hospitalization After Pediatric Cardiac Surgery. Pediatr Cardiol. 2023 Jan;44(1):161-167. doi: 10.1007/s00246-022-03016-6. Epub 2022 Sep 29. PMID: 36173454.

Kihtir HS, Duyu M, Mementoglu ME, Tolunay I, Kendirli T, Ekinci F, Botan E, Ongun EA, Asik A, Gun E, Ucmak H, Sevketoglu E, Yildizdas D. Citrate Anticoagulation in Continuous Renal Replacement Therapy: Multicenter PICU Study of Filter-Related Outcomes. Pediatr Crit Care Med. 2025 Feb 1;26(2):e216-e226. doi: 10.1097/PCC.0000000000003661. Epub 2024 Dec 19. PMID: 39699267.

Akçay N, Bingöl İ, Tosun D, Umur Ö, Çitak A, Başak G, Şik G, Telhan L, Kangin M, Menentoğlu ME, Şevketoğlu E, Tuğrul HC, Bilgün C, Bayraktar S, Duyu M, Aşik A, Özel A, Tosun V, Aygüler E, Botan E, Bursal B, Yüce S. Severe Influenza Virus Infection After COVID-19 Pandemic: Comparison of Influenza A and Influenza B. Pediatr Infect Dis J. 2025 Mar 21;44(8):e278-e284. doi: 10.1097/INF.0000000000004801. PMID: 40168599.

Botan E, Gün E, Beşli Çelik D, Gurbanov A, Balsak S, Balaban B, Kahveci F, Özen H, Uçmak H, Gençay AG, Kendirli T. Corrigendum to 'The Evaluation of Transported Children to Pediatric Intensive Care Unit: Indications, Problems and Outcomes' [Air Medical Journal 40/4 (2021) 237-241]. Air Med J. 2021 Nov-Dec;40(6):459. doi: 10.1016/j.amj.2021.07.005. Epub 2021 Aug 5. PMID: 34794790.

Aslan M, Dogan M, Celik O, Karsavuran N, Doğan DG, Botan E, Alkan A, Catal F, Celik E. Comparison of brain apparent diffusion coefficient value in naturally and assisted conceived newborns. J Matern Fetal Neonatal Med. 2012 Dec;25(12):2762-5. doi: 10.3109/14767058.2012.703713. Epub 2012 Jul 10. PMID: 22738175.

Botan E, Kendirli T, Gün E, Balsak S, Ramoğlu M, Tutar E. Cardiac arrest due to a fatal dose of propranolol successfully treated with intravenous lipid infusion. Turk J Pediatr. 2021;63(5):913-916. doi: 10.24953/turkjped.2021.05.020. PMID: 34738374.

Aydın B, Botan E. A newborn with anaphylaxis due to vancomycin. Turk J Pediatr. 2022;64(6):1146-1150. doi: 10.24953/turkjped.2021.1941. PMID: 36583898.

Boyraz M, Yüce S, Örmeci MT, Botan E. Thrombosis secondary to penetration of internal carotid artery due to soft palate impalement injury: A case report of hemiplegic syndrome and literature review. Int J Pediatr Otorhinolaryngol. 2024 Jan;176:111809. doi: 10.1016/j.ijporl.2023.111809. Epub 2023 Nov 30. PMID: 38096745.

Kahveci F, Kendirli T, Gurbanov A, Botan E, Koloğlu M, Bektaş Ö, Kuloglu Z, Balcı D, Kansu A. Tacrolimus toxicity-related chorea in an infant after liver transplantation. Acute Crit Care. 2022 Aug;37(3):477-479. doi: 10.4266/acc.2021.01431. Epub 2022 Aug 17. PMID: 35977888.

Ekinci F, Yildizdaş D, Özgür Horoz Ö, Yilmaz HL, Bilen S, Ünal İ, Türker İ, Şevketoğlu E, Akçay N, Çitak A, Şik G, Kendirli T, Havan M, Kangin M, Talay MN, Yener N, Albayrak H, Botan E, Özer U, Oto A, Bozan G, Duyu M, Akyildiz BN, Gökay N, Çelik E, Konca Ç, Yazici MU, Dursun O, Inceköy Girgin F, Ari HF, Arslan İ, Özkale M, Sandal Ö, Misirlioğlu M, Keskin H, Kaya S, Kilinç A, Sari F, Akin F, Aşik A, Bingöl İ, Turanli E, Boyraz M, Dinleyici EÇ, Dündar MA, Özcan SC, Kaya Akilli A, Akkuzu E, Ülgen Tekerek N, Öztürk N, Gün E, Özkale Y, Kutlu NO, Öztürk Z. Multiple organ dysfunction syndrome in pediatric colchicine poisoning: a national cohort study from Türkiye. Turk J Med Sci. 2026 Feb 4;56(3):708-717. doi: 10.55730/1300-0144.6204. eCollection 2026. PMID: 42499431.

Boyraz M, Yüce S, Kızıltan GF, Turgut HC, Bayramlar OF, Botan E. Clinical warning signs preceding severe suicide attempts requiring pediatric intensive care in children and adolescents. Front Psychiatry. 2026 Jul 27;17:1881780. doi: 10.3389/fpsyt.2026.1881780. eCollection 2026. PMID: 42577637.

Botan E, Boyraz M, Yüce S, Tuğrul HC, Gün E, Erdem Torun Ş, Özen H, Havan M, Aşık A, Gurbanov A, Karadağlı EE, Ulu Botan E, Köker A, Yavuz S, Arı HF, Duyu M, Horoz ÖÖ, Ekinci F, Dursun O, Yıldızdaş RD, Kendirli T. Impact of Immunotherapy Combinations on Clinical Outcomes in Children with Acute Flaccid Paralysis: A Multicenter Intensive Care Study. Turk Arch Pediatr. 2026 Aug 26;61(10):911-918. doi: 10.65717/TurkArchPediatr.2026.25350. PMID: 42826237.

Uçmak H, Havan M, Gurbanov A, Balaban B, Kahveci F, Özen H, Botan E, Gün E, Durak Aslan A, Eyduran E, Bektaş Ö, Eser Elçin A, Kendirli T. Mesenchymal stem cell therapy as adjunctive treatment in pediatric patients with severe acquired brain injury: a single-center retrospective case series. Front Pediatr. 2026 Jul 14;14:1859885. doi: 10.3389/fped.2026.1859885. eCollection 2026. PMID: 42523973.

Botan E, Gün E, Şen EK, Yöndem C, Gurbanov A, Balaban B, Kahveci F, Özen H, Uçmak H, Gençay AG, Kendirli T. Correction: Characteristics and timing of mortality in children dying in pediatric intensive care: a 5-year experience. Acute Crit Care. 2026 Aug;41(3):718. doi: 10.4266/acc.2022.00395.e1. Epub 2026 Aug 31. PMID: 42723460.

Gün E, Botan E, Bektaş Ö, Kendirli T. Toxic Brain Edema and Brain Death After Scorpion Envenomation. Wilderness Environ Med. 2021 Jun;32(2):260-261. doi: 10.1016/j.wem.2021.01.006. Epub 2021 May 7. PMID: 33966969.